2023.11.23 06:43What should be paid attention to when introducing fluorescent modification into peptides?Introducing fluorescent modifications into peptides is a common strategy in biochemistry and molecular biology for visualizing and studying the behavior of peptides in biological systems. However, there are several considerations and best practices that should be taken into account when working with fluorescently labeled peptide...
2023.11.13 07:02What should be paid attention to when designing phosphorylation-modified peptides?Designing phosphorylation-modified peptides requires careful consideration of various factors to ensure the success of the experiment and the relevance of the obtained data. Here are some key aspects to pay attention to when designing phosphorylation-modified peptides:1.Identification of Phosphorylation Sites:Literature Review: ...
2023.11.09 02:18How many types of D-type natural amino acids are there?In the context of natural amino acids, D-type amino acids refer to enantiomers of the standard L-amino acids. Enantiomers are molecules that are mirror images of each other but cannot be superimposed. L-amino acids are the primary building blocks of proteins, while D-amino acids are relatively rare in biological systems. There a...
2023.11.06 02:51Why do polypeptides undergo N-terminal acetylation and C-terminal amidation modification?N-terminal acetylation and C-terminal amidation are common post-translational modifications (PTMs) that can occur to polypeptides and proteins in eukaryotic organisms. These modifications serve various functional purposes and are important for the stability, activity, and localization of the proteins. Here's a brief explanation ...
2023.11.02 05:12What amino acids are commonly used in Linker?Linkers are often used in the context of bioconjugation, where they connect or link various biomolecules, such as proteins, peptides, or drugs, to achieve specific goals like controlled drug release, improved targeting, or the creation of fusion proteins. The choice of amino acids in the linker sequence depends on the intended p...
2023.10.31 06:22What are the advantages of PEG-modified peptides?PEG-modified peptides, which involve attaching polyethylene glycol (PEG) molecules to peptide chains, offer several advantages that make them valuable in various biomedical and pharmaceutical applications. Some of the key advantages of PEG-modified peptides include:1.Improved Solubility: PEGylation can enhance the solubility of ...