Phage display is a powerful technique that has transformed modern biology and drug discovery. By displaying peptides or proteins on the surface of bacteriophages, this technology allows researchers to screen vast molecular libraries rapidly and efficiently. It plays a critical role in identifying high-affinity ligands for a wide range of targets, including antibodies, enzymes, and receptors.
What is Phage Display?
In essence, phage display links genotype to phenotype by incorporating DNA sequences encoding peptides or proteins into the phage genome. These foreign sequences are expressed on the phage’s coat protein, enabling researchers to “display” millions to billions of variants in a single library. Through iterative selection rounds—known as biopanning—target-binding clones can be isolated with high specificity.
Applications of Phage Display
Phage display technology has far-reaching applications in fields such as:
Drug discovery: Identifying peptide leads, inhibitors, and antibody fragments.
Diagnostics: Developing high-specificity binding agents for disease markers.
Vaccine development: Selecting immunogenic epitopes.
Target validation: Studying interactions between proteins, peptides, and small molecules.
KS-V Peptide’s Advanced Phage Display Services
At KS-V Peptide, we offer cutting-edge phage display services that empower researchers to accelerate discovery and development. Our services include:
Construction and screening of custom phage libraries (linear, cyclic, random, or targeted peptide libraries).
Affinity selection and enrichment for high-affinity binders.
DNA sequencing and data analysis for clone identification.
Optimization and synthesis of selected peptides for further research or therapeutic development.
Leveraging years of expertise in peptide science, our platform ensures high throughput, reproducibility, and full technical support throughout the project cycle. Whether your focus is therapeutic, diagnostic, or academic, KS-V Peptide provides tailored solutions to meet your research goals.
Partner with Us
Explore how phage display can advance your next research breakthrough. To learn more, visit our Phage Display Services page.
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